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The JA- and MYC-dependent pathway does not play a major role in the expression of mechanosensitive TCH genes, however, indicating that mechanotransduction is regulated by other signaling pathways

One notable study published in the journal Hepatology found that patients with non-alcoholic fatty liver disease who received intravenous glutathione experienced significant reductions in liver enzyme levels compared to those who received a placebo

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Current pharmacological interventions primarily target acetylcholine deficiency and amyloid plaque formation, but offer limited efficacy and are often associated with adverse effects