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Notably, endogenous GHK-Cu levels in human plasma are age-dependent, dropping from ~200 ng/mL at age 20 to below 80 ng/mL after age 60

[DOI] [PubMed] [Google Scholar] 28.Zhu X, Yu Z, Feng L, et al

(28) revealed a significant reduction in the concentrations of Bub1 and BubR1 in the oocytes of women over the age of 37, as compared to those in women under the age of 32

Moreover, it is essential to inform patients about the significance of avoiding self-medication with herbal remedies while undergoing conventional pharmacological therapy, as well as the possible risks of interactions (245247)