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Because periodic blood monitoring is required for many anticoagulants, such as INR, PT, or aPPT, the healthcare provider must emphasize the importance of completing these labs and attending their scheduled visits (15,11)

Importantly, TA1 is not approved by the FDA for autoimmune treatment, so patients should seek medical supervision and consider legal implications

2025) Methylmalonic acid and neurology MMA accumulation following decreased conversion of methylmalonyl-CoA to succinyl-CoA also impairs TCA cycle flux