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One practical note the NHS is clear on: if you are planning a pregnancy, take folic acid from before conception until the twelfth week

Yan Y, Chen Q, Dai X, Xiang Z, Long Z, Wu Y, et al

However, these tumours do not exhibit the characteristic biphasic pattern of melanin-producing, keratin-positive epithelial cells, nor do they show the synaptophysin-positive neuroblast-like cells, which are key features of melanotic neuroectodermal tumour of infancy (Thompson et al., 2025)