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Description

6 (IEC-6 cells) (iCell-r016, iCellbioscience, Shanghai, China) were cultured in DMEM medium (Gibco), supplied with 10% foetal bovine serum (FBS, Gibco) and 0.1U/mL insulin (MedChemExpress, MCE, Monmouth Junction, NJ, USA) based on ATCC protocol

Stop use for 5 days or if bleeding starts

273 Using the lipid overload oxidative stress-related calcification model, it was found that the downregulation of p53 expression suppressed GPX4 and SLC7A11 expression and decreased the GSH/GSSG ratio, thereby promoting lipid peroxidation and ferroptosis