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Description

For example, octanal is present in mouse and human plasma and increases with a high-fat diet

Lipid peroxidation generates hydroperoxides as well as endoperoxides, which undergo fragmentation to produce a broad range of reactive intermediates called reactive carbonyl species (RCS) such as isoprostanes (IsoPs), neuroprotanes, malondialdehyde, unsaturated aldehydes including 4-hydroxy-2- trans -nonenal (HNE), 4-hydroxy-2- trans -hexenal (HHE), and 2-propenal (acrolein), with different degrees of reactivity (Porter et al., 1995