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Rather surprisingly, this suggests that the benefits of reduced mTORC1 signaling, and increased autophagy may be mediated primarily by an A-independent mechanism and moreover, previous studies have demonstrated that mTORC1 inhibition leads to the suppression of tauopathy 65,66

doi: 10.11604/pamj.supp.2020.35.2.22877 36 BhatSASinghNTrivediAKansalPGuptaPKumarA

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Quantitative RT-PCR Quantitative RT-PCR (QPCR) was used to detect the mRNA level and was performed as described previously [37]