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5 Conclusions This systematic review provides compelling evidence for the clinical utility of DNA-TG as a marker for therapeutic drug monitoring of thiopurines

Pyrethroids Pyrethroids are the synthetic analogues of natural insecticidal esters of chrysanthemum acid, called pyrethrins, which are categorised into types I and II based on their physical properties and toxicities

Furthermore, most studies are comparative investigations with other autoimmune pathologies such as rheumatoid arthritis (RA) or psoriasis 22,23,24,25,26 and will be mentioned in the discussion section of this article

This intersection between TGF-1 signaling, redox imbalance, and immune dysregulation underscores the multifaceted role of the cytokine in sustaining the systemic, multi-organ pathology characteristic of CIRS