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Although preclinical evidence suggests that GLP-1RAs can cross the blood-brain barrier (BBB), the efficacy of CNS delivery and the precise therapeutic dosage necessary to achieve neuroprotective concentrations in people are unclear

The mechanism of action of TCM in the treatment of AMS is mainly through the regulation of HIF-1/NF-B signaling pathway, inhibition of inflammatory response and oxidative stress, and enhancement of energy metabolism

This study reviews the phytochemistry, pharmacology, and clinical applications of C