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HUBERMAN: In order to find out the lethal dose of something, as you can imagine, unfortunately, the way these studies are done is they give animals more and more, that is higher and higher doses of a given compound, find out at what point about 50% of the population of those animals starts to die, and then that's the so-called LD50, or at least that's one crude way of describing it

If gut repair is your primary goal, these markers help you track progress

This is why including B12 in the compound is medically justified, not merely cosmetic

Researchers initially investigated it as a potential treatment for obesity and metabolic disorders