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(2,2-Difluoro-ethyl)-[3-(10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-methyl-amine is pharmaceutical composition comprising a free base or a salt of a pharmaceutically acceptable acid other than hydrochloric, preferably without limitation nitric, sulfuric, methanesulfonic, ethylsulfonic, hydroxyethanesulfonic, sulfosalicylic, ethanedisulfonic, methylsulfuric, or trifluoroacetic

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2009) more particularly autosomal dominant polycystic kidney disease (ADPKD), the most common polycystic kidney disease and very common genetic kidney disease characterized by the formation of cysts in the kidneys (Ishimoto et al

Dopamine acts as a sort of gatekeeper of glutamatergic input, boosting strong glutamate signals while suppressing weaker ones (Horvitz, 2002)