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This specific sequence confers on the peptide a strong, stable affinity for copper, which researchers cite as the basis for its classification as a copper-peptide complex rather than a standalone peptide

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B12 injections bypass the digestive system, making them particularly valuable for individuals who cannot absorb the vitamin adequately through oral supplementation

The concept that binding proteins existed for peptide hormones like the IGFs, similar to those for steroid and thyroid hormones, were suggested by studies from Zapf and Froesch (12) and by Hintz (13), demonstrating that NSILA was present in high molecular weight complexes in serum