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GSTP1/P2 immunodetection showed a homogeneous staining across the hepatic lobule in the normal liver while the expression appeared mainly concentrated in periportal hepatocytes at 6 and 48 h in regenerating livers (Figure 1c)

N-(carboxymethyl) lysine and N-(carboxyethyl) lysine are glycoxidation products and are significantly increased by diabetes, with the typical complication being cataracts in both rats and humans (78)

However, most of the natural products presented showed an indirect effect and lack isoform selectivity, which may limit their development into clinical use

As we age, tendons stiffen, gut barrier function deteriorates, wound healing slows, and chronic low-grade inflammation ("inflammaging") erodes organ function