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Acknowledgments We are grateful to the patients and clinical staff (Xiaojing Dong, Xingwei Jiang, Xiaolin Gan, and Xiaojiao Li) from the department of obstetrics and gynecology department (The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China) for their generous contributions to this study

First, the hydroxyl group of SA 2BA is within hydrogen bond distance from the catalytic His 18, while Ser 15 is too far for interaction

tumors of the central and peripheral nervous system, including astrocytomas, neuroblastoma, glioma, and schwannoma

We could even observe change in erythrocyte debris from a group of colourless debris with a few dark brown SHGs to a group with increasing number of dark brown SHGs, which marked the gradual process of utilization of erythrocyte debris to form more new SHGs (Supplementary Fig