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Indeed, menadione can be reduced non-enzymatically by glutathione (Extended Data Fig

10.1016/j.biopha.2021.111661 328 MiyakeS.KimS.SudaW.OshimaK.NakamuraM.MatsuokaT.et al

doi: 10.1016/j.ejps.2016.04.003 186 AfifiAMSaadAMAl-HusseiniMJElmehrathAONorthfeltDWSonbolMB

Oral in the treatment of anemia due to insufficient dietary intake of vitamin B 12 in strict vegans : pour the contents of the ampoule into a glass of water