e3 ubiquitin ligases mitophagy copd smoking or cigarette smoke Impaired in COPD. In regular conditions, smoke- Tobacco toxins trigger bone marrow
Tobacco toxins trigger bone marrow mesenchymal stem cells aging by inhibiting mitophagy ScienceDirect Full article: Mitochondrial alterations during oxidative stress in chronic obstructive pulmonary disease Disruption of the Molecular Regulation of Mitochondrial Metabolism in Airway and Lung Epithelial Cells by Cigarette Smoke: Are Aldehydes the Culprit? Targeting E3 ubiquitin ligases and their adaptors as a therapeutic strategy for metabolic diseases Experimental & Molecular Medicine
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