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Gastro-intestinal symptoms score was assessed based on the score of Adam and collaborators 16 as follows: Parents were asked to indicate whether their children had experienced specific GI symptoms nausea, vomiting, bloating, abdominal cramps, early satiety, eructation or heartburn, loss of appetite, retrosternal discomfort and epigastric pain or abdominal pain over the past month

Often, the first approach is to use endoscopy to look for obvious signs of a bleed

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Anita Clayton has been a principal investigator in the clinical development of bremelanotide (PT-141) for female sexual dysfunction, leading multiple Phase 2 and Phase 3 trials that established the efficacy and safety profile supporting FDA approval