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GPX4 uses GSH as an essential cofactor to prevent lipid peroxide and maintain redox homeostasis ( The FSP1-CoQ10 Pathway Independent of GPX4 regulatory pathway, the FSP1-CoQ pathway is a novel ferroptosis pathway identified by Doll et al

Two mammalian bombesin-like peptides (BLPs) having a widespread distribution in the central nervous system (CNS) and gastrointestinal (GI) tract [47] were discovered so far: gastrin-releasing peptide (GRP), with a higher affinity towards G-protein-coupled GRP receptor, and neuromedin B (NMB) binding to the NMB receptor

Rather than supporting prescriptive conclusions, existing evidence underscores the need for mechanistically integrated, biomarker-guided approaches tailored to cancer stage, treatment exposure, and functional status

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