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The ones generating the most research interest share specific properties: they modulate inflammation, promote tissue regeneration, stimulate collagen synthesis, or support nerve healing

Another theory posits that the distress associated with a cancer diagnosis may contribute to altered cognitive function and eventually lead to depression and anxiety (Hess 2007)

Box A: Diversity of GPCR ligands Neurotransmitters norepinephrine adenosine histamine serotonin dopamine cannabinoids opiates acetylcholine GABA glutamate Peptide hormones endothelin glucagon angiotensin II GSH, FSH, CRH GnRH, ACTH Tastants, oderants, light Session Learning Objectives Learning objective 1

There may be some amount of discomfort during the administration which is usually tolerable