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Imidazole,.alpha.-diphenylbenzyl)- 221

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The diminished activity with maleylacetone results from a low turnover number C174A - mutant displays significant decrease in 1-chloro-2,4-dinitrobenzene activity C32Y O43708, Q9H4Y5, Q16772, P09211, P09210, P08263, P09488, O15217, P28161, Q03013, P46439, P78417, O60760, Q7RTV2, P21266, P0CG30 naturally occuring mutation at the primary active site residue, the rare C32Y substitution is identified in Europeans and appears to degrade rapidly