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While prolonged and repeated use of doxycycline is not recommended while breastfeeding, it's generally considered safe for short-term use

In preclinical studies, the compound is being examined for its growth factor signaling, cellular proliferation, and metabolic pathway regulation

Current clinical guidelines recommend (Fraenkel et al, 2021

Vitamin D plays a very prominent role in immune responses and low vitamin D status is often described in the context of autoimmune and inflammatory diseases