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Description

2- Chlorodeoxyadenosine therapy for idiopathic hypereosinophilic syndrome

One of the best-known examples of a peroxidase-based redox relay is the yeast glutathione peroxidase-like enzyme Orp1 (Gpx3), which transfers oxidative equivalents to the yeast oxidative stress transcription factor Yap1 via the formation of an intermolecular disulfide bond [108110]

These findings are entirely consistent with data obtained by other investigators in vivo in the mouse and in vitro using isolated mouse hepatocytes (Rashed et al