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But here are some general guidelines: Severe deficiencies: Daily shots for 1 week, then weekly shots until levels normalize Moderate deficiencies: Weekly shots until the deficiency is corrected Maintenance dosing : Monthly shots to keep B12 levels optimal Its definitely possible to take B12 shots too often

Stomach acids will break down B-12 taken orally, limiting the amount of usable B-12 your body will be able to absorb

For example, myocardial dysfunction has been linked to mitochondrial dysfunction caused by copper deficiency-induced expression of molecules related to mitochondria (100)

Given that the binding of IGF-1 to IGFBPs is reversible and that the ratio of cGP:IGF-1 appeared to determine the efficacy of cGP, we tested the possibility for cGP to alter the binding of IGF-1 to IGFBP-3