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This relationship seems to be explained in part by a reduction in insulin-like growth factor 1 (IGF-1, a key driver of fetal growth) levels, as observed in cord blood of fetuses exposed to maternal tobacco smoking 17

Changes in chromatin arrangement caused by acute cigarette smoke stress limited the ability of young and aged mouse RPE cells to function, and replicated characteristics seen in humans with age-related macular degeneration, the researchers say