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Description

Patients with MS can present with a variety of neurological dysfunctions, including ataxia, dexterity loss, myoclonus, spasticity, paraparesis or hemiparesis, vision loss and cognitive deficits, depending on the different pathways involved

Statistics Graphs and statistical analyses were performed in GraphPad Prism, version 9.2.0 ( Statistical analyses were performed using Welch t-test for single-pair comparisons or one-way ANOVA with post hoc Tukeys or Dunnetts tests for multiple comparisons, where applicable

Itoh is also conducting a phase II study (UMIN000030609) to assess the safety of long-term NMN in healthy subjects, the kinetics of NMN and metabolites of NAM, and the effect of daily administration of NMN on glucose metabolism