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J Hepatol 34(1):1925

Report any unusual or persistent symptoms to your care team, and seek prompt medical attention for severe reactions such as difficulty breathing, chest pain, or signs of an allergic reaction

(8) Long-term vitamin B12 deficiency can cause permanent nerve damage and neurological symptoms

Together, these findings suggest that checkpoint activation could indirectly influence ferroptosis-associated pathways in AD, yet the connection remains inferential, underscoring the need for future multi-omics and spatial single-cell studies in human brains to validate this link