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Materials and methods Animal models In these studies, APOE-TR mice were housed in groups of up to four under standard laboratory conditions at 23 1C, 50 5% humidity, with a 12-h light/dark cycle and access to food and water ad libitum

Since single-cell omics analyses can identify cellular heterogeneity within tissues, they have grown in popularity to preserve this information (194)

This differential tissue regulation of these enzymes results in increased BCAAs in adipose tissue, a decrease in liver BCAAs and no change in skeletal muscle

All patients were examined in each center by a certified urologist specialized in male sexual dysfunction who evaluated the adverse events (AEs) and assisted patients to fill the questionnaires at the baseline and at the control visit