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LPO is defined as an oxidative process in which lipid molecules, particularly PUFAs, are oxidized to generate peroxides and constitutes a core mechanism of ferroptosis

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In addition, other residues have been identified and successfully used to replace the phosphodiester group in oligonucleotides and change the properties of intact strands, including phosphorodithioate (PS2), 54 methylphosphonate (MP), methoxypropylphosphonate (MOP) and peptide nucleic acid (PNA) (Fig

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