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Chemical modifications to mRNA nucleobases impact translation elongation and termination

Pasqualotto EB, Agarwal A, Sharma RK, Izzo VM, Pinotti JA, Joshi NJ, et al

The risk of developing gout in those with asymptomatic hyperuricemia increases with higher serum urate level, and has suggested to be ~20% at 5 years in those with a serum urate of 9 mg/dL