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However radiolabeled agents do not provide information regarding enzyme activity as they accumulate at the tumor site by diffusion, and the utility of fluorescent probes is limited by the depth of fluorescent light penetration through the skull

One of its main functions is to act as a cofactor for enzymes that are responsible for clotting the blood ( Without vitamin K, the blood would lose its ability to clot properly, increasing the risk of excessive bleeding

Proc Natl Acad 79:21722175

YAP1 over-expression in Saccharomyces cerevisiae enhances glutathione accumulation at its biosynthesis and substrate availability levels