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In addition, drug metabolism and pharmacokinetics differ significantly across species, resulting in variations in efficacy and toxicity profiles

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According to the research of Javanmanesh et al., in compare to metformin, receiving NAC at a dose of 1800 mg per day for 6 months decreased the level of FBS, insulin, HOMA-IR, and serum TG in women with polycystic ovary syndrome (PCOS), but it had no effect on their other lipid profiles (34)