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It catalyzes the reduction of hydrogen peroxide (H2O2) and a variety of organic hydroperoxides (R-O-O-H) to water and the corresponding stable alcohols (R-OH) using glutathione as the reducing reagent, thus inhibiting the formation of free radicals and protecting the cells from oxidative damage

10.1007/s10616-019-00329-y 4 ArtsI

Here, we explored targeting key antioxidant pathways to induce ferroptosis, as we observed a prognosis-correlated high expression across multiple NB patient cohorts

Figure 5: The Fluorescence spectra recorded during H 2 O 2 calibration that shows a decrease in QD fluorescence intensity with stepwise addition of H 2 O 2 solution