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Lipoproteins such as Low-density lipoproteins (LDL) and high-density lipoproteins (HDL) are mainly responsible for the transport of lipids such as cholesterol and triglycerides (117)

Dose-dependent activity: Low doses (25-100 mg): Mostly hypnotic/sedative effects via 5-HT2A, H1, and alpha-1

One can determine the LD 50 (the dose lethal to 50% of the population) and the ED 50 (the dose therapeutically effective in 50% of the population) using procedures presented herein and those otherwise known to those of skill in the art

(Faisal and Mustafa, 2025) Capsicum extract is rich in several biologically active constituents: Capsaicin acts primarily on the transient receptor potential vanilloid 1 (TRPV1) receptor, a nociceptor involved in thermoregulation and pain perception