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As it was mentioned above, smokers, who are smoking about a pack per day are exposed about 600 times per month and approximately 7000 times per year for these warnings Based on this it can be suggested that the heavy smokers develop a habituation and immunity to the warnings due to their familiarity with the warnings

Varenicline works by stimulating nicotine receptors in the brain, which helps to reduce withdrawal symptoms and cravings without delivering nicotine

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