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Am J Physiol Gastrointest Liver Physiol 318:F354F362

10.1158/1078-0432.CCR-07-1416 151 HuZ.CaiM.ZhangY.TaoL.GuoR

The coordination and balance between Th17 cells and Tregs enables the maintenance of standard immune functionality within the body (99)

Furthermore, through mechanisms such as acidification of the microenvironment, this metabolic shift fosters an immunosuppressive environment favorable for tumor survival, thereby significantly increasing the invasive and metastatic potential of tumor cells [19]