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Considerations when helping an individual to select an appropriate form of pharmacotherapy to quit include: previous experience with pharmacotherapy cost and convenience adherence issues (eg individual preferences for a patch or gum, one or more forms of NRT, non-nicotine options) prescription medicine versus over-the-counter medicine potential for adverse events possible drugdrug interactions

Combining the two substances can intensify the effects of both drugs, leading to an increased heart rate, blood pressure, and anxiety