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Throughout the 0-32 week treatment period, adverse outcomes and the occurrence of anti-cagrillintide antibodies were assessed in addition to any changes in systolic and diastolic blood pressure, pulse rate, plasma high-sensitivity C-reactive protein, aldosterone, and the activity of renin

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Mechanisms of primary and/or acquired resistance include tumor-related factors, such as reduced cell surface expression levels of the target antigen and high levels of complement inhibitors (CD55 and CD59)