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Next, we constructed a gene-disease association network for 9 liver disease terms using the data from four public databases: the Online Mendelian Inheritance in Man (OMIM) database (December 2012) 21 , HuGE Navigator 22 , PharmGKB 18 and CTD 15 (Figure 1B)

The imbalance between ROS production and antioxidant capacity, including catalase, contributes to lipid, protein, and DNA oxidative damage, exacerbating cardiovascular disease [68]