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It has been reported that the CPT1C isoform is overexpressed in human tumor cells such as neuroblastoma, several sarcomas of soft-tissues and lung, and malignant peripheral nerve sheath tumors (associated with neurofibromatosis type 1) 45

While no evidence of CVS association was obtained from our participants, OTC did have the highest numbers of points of any gene (Table 1), completely derived from our literature review