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Such cramps may come during the activity or later, sometimes many hours later

Clin Pharmacokinet 2016;55:1395-411

Furthermore, the immunohistochemistry analysis evaluated the protective effects of the Au-PX-PLGA on dopaminergic neurons in the striatum and tyrosine hydroxylase, which is an essential enzyme in dopamine synthesis, served as the biomarker for dopaminergic neuron integrity