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When you smoke tobacco products containing nicotine, it enters your lungs and then diffuses into the bloodstream where it travels throughout your body before being absorbed by tissues such as those found in the brain.[1] The amount of time it takes for any drugincluding nicotineto reach peak levels depends on many factors including: That number comes from how nicotine is absorbed by your body

Flavor choices also vary, as women tend to favor fruit or dessert profiles, while men lean more toward tobacco and menthol options

2 weeks to 3 months later Heart attack risk dramatically drops

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