low glutathione reductase The above diagram illustrates the redox buffering reaction of the disulfide reductase File:Reductive half-reaction of glutathione reductase.png

Ethics statement The animal study was approved by the Institutional Animal Care and Use Committee of The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

Glutathione is not found directly in foods, but some foods contain substances necessary to increase the body's glutathione production

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It is noteworthy that NAC has also been proposed as a substitute for ibuprofen for post-endodontic pain,33 and exerts anti-inflammatory activity through its ability to inhibit the expression and release of a variety of proinflammatory cytokines.34,35 All these observations demonstrate that NAC has the potential to be developed as an alternative intracanal medicament