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VEGF seems to be a signaling protein, reportedly involved in angiogenesis, a process that may be responsible for the formation of new blood vessels from existing vasculature

Clinicians working with patients who have compromised gut barrier function, often framed as increased intestinal permeability or "leaky gut," sometimes extend oral BPC-157 protocols to ten to twelve weeks given the chronicity of the underlying pathology

Suppliers offering stock formulations can reduce this to 30-45 days total

The thinking is that by concentrating the peptide in the inflamed or damaged areabe it the lower back near the compressed nerve root or the gluteal area for piriformis syndromeyou maximize its local effects before it enters systemic circulation