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FIGURE 1 Beta-amyloid, and especially tau, compounds have primarily been associated with Alzheimers disease

doi: 10.1016/j.cell.2024.05.031 385 WuD.BiX.ChowK

Also, in vitro studies indicate that the responsiveness of pro-B cells to IL-7 is compromised in aged individuals [355], and IL-7 release from stromal cells in the bone marrow also declines with age [356], leading to reduced pro B-cell proliferation