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In the absence of vitamin B12 supplementation, unusually high vitamin B12 levels in the bloodstream may sometimes indicate underlying health conditions, including: 10 Several forms of liver disease, such as acute hepatitis, cirrhosis, and liver cancer Certain blood cancers, including leukemia and polycythemia vera Hypereosinophilic syndrome, a group of blood disorders that may lead to organ damage 11 Does Having High Vitamin B12 Levels Mean Cancer

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The predictors of pemetrexed toxicities were poor Eastern Cooperative Oncology Group performance status (ECOG-PS) and low body mass index (BMI) for febrile neutropenia (FN), concomitant chronic infectious disease, bevacizumab use for neutropenia, poor ECOG-PS for thrombocytopenia, and low serum albumin levels for non-hematologic toxicities

Following centrifugation at 16,200 g for 20 min at 4 C, the supernatant was collected and directly injected into the analytical HPLC (final concentration: 50 M)