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We also analyzed the levels of aspartate transaminase (AST) and alanine transaminase (ALT) after hepatocyte injury

Given the prior benefits we observed for NAC in our Seahorse assays, we tested if NAC could restore intracellular GSH, which it did (Fig

doi: 10.1038/s41598-022-11236-2 Summary Keywords metformin, rectal cancer, colorectal, radiosensitiser, energy metabolism, radioresistance Citation Buckley CE, OBrien RM, Nugent TS, Donlon NE, OConnell F, Reynolds JV, Hafeez A, ORordin DS, Hannon RA, Neary P, Kalbassi R, Mehigan BJ, McCormick PH, Dunne C, Kelly ME, Larkin JO, OSullivan J and Lynam-Lennon N (2023) Metformin is a metabolic modulator and radiosensitiser in rectal cancer