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Hattori K, Ishikawa H, Sakauchi C, Takayanagi S, Naguro I, Ichijo H (2017) Cold stress-induced ferroptosis involves the ASK1-p38 pathway

This article is the first in a four-part series that reviews recent literature on cutaneous adverse reactions experienced with commonly prescribed biologic and targeted therapies, specifically tumor necrosis factor (TNF) alpha inhibitors, epidermal growth factor receptor (EGFR) inhibitors, small-molecule tyrosine kinase inhibitors (TKIs), and frequently used cell surface-targeted monoclonal antibodies

3.1 Trxs The cytosolic Trx system might directly protect against ferroptosis by reducing lipid hydroperoxides (Figure 3)

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