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5-Amino 1MQ and NNMT Inhibition

International Journal of Neuropsychopharmacology 14 :1069-1074

Splicing-directed therapy in a new mouse model of human accelerated aging

Estrogens could positively affect dopamine neurotransmission by reducing the expression of catechol-O-methyltransferase (COMT), the enzyme responsible for dopamine degradation (Jiang et al., 2003)