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The results demonstrated a 90-95% reduction in the average levels of harmful and potentially harmful constituents (HPHCs) compared with reference cigarette (3R4F) smoke and fewer chemicals in the aerosol than in cigarette smoke.(1) Three chemicals were identified in the aerosol of THS that were not in the smoke from the reference cigarette, but all of these chemicals have previously been reported in the smoke of marketed cigarettes

1 This widely cited statistic, however, is an underestimate, as it only considers deaths from 21 diseases that have been formally recognized as caused by cigarette smoking

Their ratio remains nearly unchanged regardless of the tobaccos origin

Almost one in twenty American adults now use e-cigarettes