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TB-500 and bone repair Thymosin beta-4 (TB-500) is a 43-amino-acid peptide involved in cell migration, blood vessel formation, and tissue repair

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The reduction of roGFP2(S 2 ) is therefore a good example for an enzyme using an alternative reaction pathway to overcome a kinetic challenge, and we hypothesize that other non-glutathione disulfide substrates with reactive proximal cysteinyl residues and rather negative redox potentials also require a ternary complex for their reduction

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